Tuesday, May 24, 2011

Hypertension

http://www.usana.com/dotCom/company/science/conditions/condition_15930

Description

  • Hypertension, or high blood pressure, is defined in an adult as a blood pressure greater than or equal to 140 mm Hg systolic pressure or greater than or equal to 90 mm Hg diastolic pressure. High blood pressure directly increases the risk of coronary heart disease and stroke, especially along with other risk factors.1
Causes
  • Essential hypertension is of unknown etiology, but family history, obesity, high fat or high sodium diets, race, stress, and a sedentary lifestyle are all associated with hypertension.
  • Secondary hypertension is caused by an underlying factor such as kidney, endocrine, or neurological disease.
Types
  • High blood pressure can either be essential or secondary. Essential hypertension is treated with medication by physicians. Secondary hypertension is a symptom of an underlying problem. When the cause of the hypertension is corrected, blood pressure will return to normal.
At Risk
  • High blood pressure can occur in children or adults, but is particularly prevalent in blacks, middle-aged and elderly people, men, obese people, heavy drinkers and women who are taking oral contraceptives. Individuals with diabetes mellitus, gout, or kidney disease also have a higher frequency of hypertension.2
Prevention and Management
General:
  • There are many medications prescribed by physicians used to treat hypertension.
  • Dietary and lifestyle changes also may help control high blood pressure. For example, blood pressure often returns to normal in obese people who lose weight.
  • Excessive alcohol intake (more than two ounces daily) raises blood pressure in some people and should be restricted.
  • Increasing physical activity, as long as it is approved and guided by the physician, can reduce blood pressure in some people.
  • People who smoke are advised to quit because it increases the risk of high blood pressure.
Nutritional Influences:
  • Some people with mild hypertension can lower their blood pressure by reducing sodium in their diet.3 The American Heart Association recommends that healthy American adults reduce their sodium intake to no more than 2400 milligrams per day.
  • Supplemental vitamin C decreased blood pressure in borderline hypertensive and normotensive subjects.4
  • Calcium intakes of 800 mg/day were associated with lower blood pressures.5
  • Magnesium supplementation was effective with hypertensive patients.6
  • Antioxidant levels in the serum of hypertensive patients are generally lower. This may indicate that lower intakes of antioxidants increases risk for hypertension.7
Abstracts
Mark SD, Wang W, Fraumeni JF et al. Lowered risks of hypertension and cerebrovascular disease after vitamin/mineral supplementation: The Linxian Nutrition Intervention Trial. Am J Epidemiol 1996;143:658-64.A total of 3,318 men and women from a region in rural China were randomized to receive daily either a multiple vitamin/mineral supplement or a placebo. Deaths that occurred in the participants were ascertained and classified according to cause over the 6-year period from 1985 to 1991. At the end of supplementation, blood pressure readings were taken, and the prevalence of hypertension was determined. There was a slight reduction in overall mortality in the supplement group (relative risk (RR) = 0.93, 95 percent confidence interval (CI) 0.75-1.16), with the decreased relative risk most pronounced for cerebrovascular disease deaths (RR = 0.63, 95 percent CI 0.37-1.07). This benefit was greater for men (RR = 0.42, 95 percent CI 0.19-0.93) than for women (RR = 0.93, 95 percent CI 0.44-1.98). Among the survivors, the presence of elevations in both systolic and diastolic blood pressures was less common in those who received the supplement (RR for men = 0.43, 95% CI 0.28-0.65; RR for women = 0.92, 95 percent CI 0.68-1.24). This study indicates that supplementation with a multivitamin/mineral combination may have reduced mortality from cerebrovascular disease and the prevalence of hypertension in this rural population with a micronutrient-poor diet.
Tse WY, Maxwell SR, Thomason H et al. Holder antioxidant status in controlled and uncontrolled hypertension and its relationship to endothelial damage. J Hum Hypertens 1994;8:843-9. Hypertension is associated with an increased risk of atherosclerosis. Free radical oxidative damage has been implicated in the atherogenic process. We measured levels of the antioxidants uric acid, thiols, vitamins C, A and E as well as the total antioxidant capacity in 21 normotensive controls, 22 patients whose hypertension was controlled on drugs and 30 patients with uncontrolled hypertension. Mean BPs in the groups were 125/76, 132/80 and 181/98 mmHg, respectively. When compared with controls, both hypertensive groups had significantly lower serum ascorbic acid (54 +/- 5 vs. 37 +/- 6 vs. 38 +/- 5 mumol/l, P < 0.05) and albumin-corrected thiol levels (9.91 +/- 0.18 vs. 8.69 +/- 0.20 vs. 8.92 +/- 0.19 mumol/g, P < 0.05). The levels of the other antioxidants did not differ significantly between the groups. Levels of von Willebrand factor, a marker of endothelial damage, were correlated with SBP but not with antioxidant status. We conclude that hypertensive subjects have lower levels of the antioxidants vitamin C and thiols and this may reflect greater oxidative consumption. The implications for atherogenesis and endothelial function and integrity in hypertension are discussed.
References
1 Zeman FJ. Clinical Nutrition and Dietetics. 2nd Ed. New York:MacMillan Publ; 1991
2 Zeman FJ. Clinical Nutrition and Dietetics. 2nd Ed. New York:MacMillan Publ; 1991
3 Williams GH, Hollenberg NK. Sodium-sensitive essential hypertension : Emerging insights into an old entity. J Am Col Nutr 1989;8:490-94.
4 Osilesi O. Blood pressure and plasma lipids during ascorbic acid supplementation in borderline hypertensive and normotensive adults. Nutr Res 1991;11:405-12.
5 McCarron DA. Dietary calcium and blood pressure: modifying factors in specific populations. Am J Clin Nutr 1991;54:215S-19S
6 Mark SD, Wand W, Fraumeni JF et al. Lowered risks of hypertension and cerebovascular disease after vitamin/mineral supplementation: the Linxian Nutrition Intervention Trial. Am J Epidemiol 1996;1:658-64
7 Tse WY, Maxwell SR, Thomason H et al. Antioxidant status in controlled and uncontrolled hypertension and its relationship to endothelial damage. Hypertens 1994;8:843-9.

Sunday, May 15, 2011

Job Review

10 Signs It’s Time To Quit Your Job

But even in a bad economy some jobs are just not worth it. Are there any telltale signs you should be looking for when trying to decide if you throw in the towel? Here are ten signs to look for to determine if it’s time to find a new job
You Aren’t Learning Anything New
Yes, you want to know how to do most of your job. But there are also things you want to be learning; otherwise you are not growing professionally. If you have stopped learning at work, it’s time to find a job where you will learn new skills and grow professionally.
You Never Have a Day When You Wake Up Excited To Go To Work
If you wake up every morning Monday through Friday and never feel excited to go to work, that is a problem. It means you aren’t enjoying your job and it is diminishing your quality of life. If you wake up every day and dread going to work, it’s time to consider quitting your job.
You Spend More Time Surfing the Web Than Doing Your Job
When you are at work, you are supposed to be productive. Otherwise, it’s a waste of your time and the company’s money. If you are bored and surfing the web most of your work day, you may want to think about looking into job options where you’ll get more stimulation and responsibilities.
You Don’t Like Most of Your Coworkers
There are always one or two coworkers in the office that most people can’t stand. But if you don’t like most of your coworkers, chances are your days aren’t very enjoyable because you have to work with them day in and day out. If you can’t stand most of your coworkers, it’s time to think about finding a company whose employees you mesh with better.
You Aren’t Making Enough Money to Pay Your Bills
If you are working your butt off and not getting paid enough to pay your bills, you might be overqualified and underpaid for your position. Go find a job that pays what you deserve.
You Spend Time Looking For Other Jobs
If you are spending time looking for other jobs while you are on the clock, it’s obvious you want to leave your job. So keep looking for new jobs and as soon as you find a good one, take it and run.
You Haven’t Gotten a Raise in the Last Two Years
If you work hard and benefit the company you work for, you deserve to be rewarded for that. If your boss hasn’t given you a raise in the last two years, ask for one. If he or she says no, get out now.
Your Boss Sucks
Sometimes bosses suck. But if your boss sucks all the time and takes advantage of your time, it’s time to find a new job.
The Company Isn’t Doing Well
This sign varies from company to company. You must keep in mind that we are in a recession and if sales are down but the company isn’t in jeopardy, this sign may not apply to you. However, if business is down to the point where it looks like the company is going to go under, start looking for a new job NOW! 
You are Stressed All the Time
You are supposed to enjoy life, not be stressed out all the time. If you spend most of your days stressed about everything that going on at work, you are not at the right job.
Know any other signs that you should quit your job that weren’t listed above? Share them with us in the comments section!
Ashley Jacobs is the college correspondent for personal finance blog Wise Bread. Follow her latest tweets on @CollegeCents.

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